Počet záznamů: 1

Dual imaging probes for magnetic resonance imaging and fluorescence microscopy based on perovskite manganite nanoparticles

SYSNO ASEP	0358984
Druh ASEP	J - Článek v odborném periodiku
Zařazení RIV	J - Článek v odborném periodiku
Poddruh J	Článek ve WOS
Název	Dual imaging probes for magnetic resonance imaging and fluorescence microscopy based on perovskite manganite nanoparticles
Tvůrce(i)	Kačenka, M. (CZ) Kaman, Ondřej (FZU-D)_{RID, ORCID} Kotek, J. (CZ) Falteisek, L. (CZ) Černý, J. (CZ) Jirák, D. (CZ) Herynek, V. (CZ) Zacharovová, K. (CZ) Berková, A. (CZ) Jendelová, Pavla (UEM-P)_{RID, ORCID} Kupčík, Jaroslav (UCHP-M)_{RID, ORCID, SAI} Pollert, Emil (FZU-D) Veverka, Pavel (FZU-D)_{RID, ORCID} Lukeš, I. (CZ)
Zdroj.dok.	Journal of Materials Chemistry. - : ROYAL SOC CHEMISTRY - ISSN 0959-9428 Roč. 21, č. 1 (2011), s. 157-164
Poč.str.	8 s.
Jazyk dok.	eng - angličtina
Země vyd.	GB - Velká Británie
Klíč. slova	cellular labelling ; dual probe ; magnetic nanoparticles ; MRI ; silica coating
Vědní obor RIV	BM - Fyzika pevných látek a magnetismus
CEP	KAN200200651 GA AV ČR - Akademie věd
CEZ	AV0Z10100521 - FZU-D (2005-2011)
	AV0Z50390703 - UEM-P (2007-2013)
	AV0Z40720504 - UCHP-M (2005-2011)
UT WOS	000285067300019
DOI	10.1039/c0jm01258k
Anotace	The present study reveals the potential of magnetic nanoparticles based on the La0.75Sr0.25MnO3 perovskite manganite for MRI. Moreover, it describes the development of the dual imaging probe where the magnetic cores are combined with a fluorescent moiety while the improved colloidal stability is achieved by a two-ply silica shell. At first, the magnetic cores of La0.75Sr0.25MnO3 are coated with a hybrid silica layer, comprising a covalently attached fluorescein moiety that is subsequently covered by a pure silica layer providing the enhanced stability. Viability tests show that the complete particles are suitable for biological studies and the internalization occurs in different cell types. Further experiments prove no fatal interference with the vitality. Relaxometric measurements confirm high spin–spin relaxivities and visualisation of in vitro labeled pancreatic islets by MRI is successfully tested.
Pracoviště	Fyzikální ústav
Kontakt	Kristina Potocká, potocka@fzu.cz, Tel.: 220 318 579
Rok sběru	2012

Počet záznamů: 1