Počet záznamů: 1  

Early morphogenesis of heterodont dentition in minipigs

  1. 1.
    SYSNO ASEP0357737
    Druh ASEPJ - Článek v odborném periodiku
    Zařazení RIVJ - Článek v odborném periodiku
    Poddruh JČlánek ve WOS
    NázevEarly morphogenesis of heterodont dentition in minipigs
    Tvůrce(i) Štembírek, Jan (UZFG-Y) ORCID
    Buchtová, Marcela (UZFG-Y) RID, ORCID
    Král, T. (CZ)
    Matalová, Eva (UZFG-Y) RID
    Lozanoff, S. (US)
    Míšek, Ivan (UZFG-Y)
    Zdroj.dok.European Journal of Oral Sciences. - : Wiley - ISSN 0909-8836
    Roč. 118, č. 6 (2010), s. 547-558
    Poč.str.12 s.
    Jazyk dok.eng - angličtina
    Země vyd.DK - Dánsko
    Klíč. slovadental lamina ; epithelial pearls ; odontogenesis
    Vědní obor RIVFF - ORL, oftalmologie, stomatologie
    CEPGP304/08/P289 GA ČR - Grantová agentura ČR
    CEZAV0Z50450515 - UZFG-Y (2005-2011)
    UT WOS000284319400002
    DOI10.1111/j.1600-0722.2010.00772.x
    AnotaceThe minipig provides an excellent experimental model for tooth morphogenesis because its diphyodont and heterodont dentition resemble that of humans. However, little information is available on the processes of tooth development in the pig. The purpose of this study was to classify the early stages of odontogenesis in minipigs from the initiation of deciduous dentition to the late bell stage when the successional dental lamina begins to develop. To analyze the initiation of teeth anlagens and the structural changes of dental lamina, a three-dimensional (3D) analysis was performed. At the earliest stage, 3D reconstruction revealed a continuous dental lamina along the length of the jaw. Later, the dental lamina exhibited remarkable differences in depth, and the interdental lamina was shorter. The dental lamina grew into the mesenchyme in the lingual direction, and its inclined growth was underlined by asymmetrical cell proliferation. After the primary tooth germ reached the late bell stage, the dental lamina began to disintegrate and fragmentize. Some cells disappeared during the process of lamina degradation, while others remained in small islands known as epithelial pearls. The minipig can therefore, inter alia, be used as a model organism to study the fate of epithelial pearls from their initiation to their contribution to pathological structures, primarily because of the clinical significance of these epithelial rests.
    PracovištěÚstav živočišné fyziologie a genetiky
    KontaktJana Zásmětová, knihovna@iapg.cas.cz, Tel.: 315 639 554
    Rok sběru2011
Počet záznamů: 1  

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