Počet záznamů: 1
Selective recognition of a saccharide-type tumor marker with natural and synthetic ligands: a new trend in cancer diagnosis
- 1.
SYSNO ASEP 0356081 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Selective recognition of a saccharide-type tumor marker with natural and synthetic ligands: a new trend in cancer diagnosis Tvůrce(i) Kejík, Z. (CZ)
Bříza, T. (CZ)
Králová, Jarmila (UMG-J) RID
Martásek, P. (CZ)
Král, V. (CZ)Zdroj.dok. Analytical and Bioanalytical Chemistry. - : Springer - ISSN 1618-2642
Roč. 398, č. 5 (2010), s. 1865-1870Poč.str. 6 s. Jazyk dok. eng - angličtina Země vyd. DE - Německo Klíč. slova extracellular-matrix components ; hepatocellular carcinoma ; breast cancer Vědní obor RIV EB - Genetika a molekulární biologie CEP LC06077 GA MŠMT - Ministerstvo školství, mládeže a tělovýchovy GA203/09/1311 GA ČR - Grantová agentura ČR KAN200200651 GA AV ČR - Akademie věd CEZ AV0Z50520514 - UMG-J (2005-2011) UT WOS 000283244500005 DOI 10.1007/s00216-010-4124-7 Anotace It is well known that saccharides and their glycoconjugates can have an important influence on various serious pathologic stages such as cancer. They can regulate tumor proliferation, invasion, hematogenous metastasis, and angiogenesis. These facts clearly show the importance of cancer saccharide recognition. In medicine, sensor analysis is one of the best methods for recognition and determination of biologically important analytes. The development and study of sensors for saccharide tumor markers can open a new way for their detection. Therefore, this review is focused on recognition of saccharide-based cancer markers by natural or synthetic selective ligands working as bio- and chemosensors. The design and application of these ligands for cancer diagnosis is a useful direction of research. Moreover, it also opens the possibility of using these agents for the targeted drug transport required for advanced anticancer therapy. Pracoviště Ústav molekulární genetiky Kontakt Nikol Škňouřilová, nikol.sknourilova@img.cas.cz, Tel.: 241 063 217 Rok sběru 2011
Počet záznamů: 1