Počet záznamů: 1

IrML – a gene encoding a new member of the ML protein family from the hard tick, Ixodes ricinus

SYSNO ASEP	0353437
Druh ASEP	J - Článek v odborném periodiku
Zařazení RIV	J - Článek v odborném periodiku
Poddruh J	Článek ve WOS
Název	IrML – a gene encoding a new member of the ML protein family from the hard tick, Ixodes ricinus
Tvůrce(i)	Horáčková, J. (CZ) Rudenko, Natalia (BC-A)_{RID, ORCID} Golovchenko, Maryna (BC-A)_{RID, ORCID} Havlíková, S. (SK) Grubhoffer, Libor (BC-A)_{RID, ORCID}
Zdroj.dok.	Journal of Vector Ecology - ISSN 1081-1710 Roč. 35, č. 2 (2010), s. 410-418
Poč.str.	9 s.
Jazyk dok.	eng - angličtina
Země vyd.	US - Spojené státy americké
Klíč. slova	Ixodes ricinus ; tick ; ML-domain containing protein ; in situ hybridization ; gene expression ; ML (MD-2-related lipid-recognition) domain
Vědní obor RIV	GJ - Choroby a škůdci zvířat, veterinární medicína
CEP	GA524/06/1479 GA ČR - Grantová agentura ČR
	LC06009 GA MŠMT - Ministerstvo školství, mládeže a tělovýchovy
CEZ	AV0Z60220518 - PAU-O, BC-A (2005-2011)
UT WOS	000285758200020
DOI	10.1111/j.1948-7134.2010.00100.x
Anotace	Blood intake causes significant changes in ticks, triggering vital physiological processes including differential gene expression. A gene encoding Ixodes ricinus ML-domain containing protein (IrML) is one of the set of the genes that are strongly induced by blood meals. IrML belongs to the ML protein family that commonly occurs in diverse organisms and is involved in lipid binding and transport, pathogen recognition or in immune response. An IrML gene was amplified from cDNA of engorged I. ricinus females using the gene-specific primers designed on a basis of partial sequences of related genes for ML domain protein. IrML was shown to be expressed mainly in the gut, but also in salivary glands and hemolymph of all tick developmental stages. Analysis of the predicted structure of I. ricinus ML-domain containing protein and its localization in the tick body could suggest that IrML is a secreted protein and is possibly involved in tick innate immunity.
Pracoviště	Biologické centrum (od r. 2006)
Kontakt	Dana Hypšová, eje@eje.cz, Tel.: 387 775 214
Rok sběru	2011

Počet záznamů: 1