Počet záznamů: 1
A short survey on protein blocks
- 1.
SYSNO ASEP 0352274 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Ostatní články Název A short survey on protein blocks Tvůrce(i) Joseph, A.P. (FR)
Agarwal, G. (IN)
Mahajan, S. (IN)
Gelly, J.Ch. (FR)
Swapna, L.S. (IN)
Offmann, B. (CZ)
Cadet, F. (FR)
Bornot, A. (FR)
Tyagi, M. (US)
Valadié, H. (FR)
Schneider, Bohdan (BTO-N) RID, ORCID
Etchebest, C. (FR)
Srinivasan, N. (IN)
de Brevern, A.G. (FR)Zdroj.dok. Biophysical reviews - ISSN 1867-2450
Roč. 2, č. 3 (2010), s. 137-147Poč.str. 11 s. Jazyk dok. eng - angličtina Země vyd. DE - Německo Klíč. slova Protein ; bioinformatics ; structure Vědní obor RIV BO - Biofyzika CEZ AV0Z50520701 - BTO-N (2007-2013) Anotace Protein structures are classically described in terms of secondary structures. The regular secondary structures have relevant physical meaning but their recognition based on atomic coordinates has a number of limitations, such as uncertainties in the assignment of the boundaries of the helical and strand regions. Moreover, an average of about 50% of all residues are assigned to an irregular state, i.e., the coil. These limitations have led different research teams to focus on abstracting the conformation of the protein backbone in the localized short stretches and different geometric measures are being used to cluster local stretches in protein structures. These libraries of local structure prototypes are named structural alphabets. We have developed a structural alphabet, denoted protein blocks, not only to approximate the protein structures but also to predict them from the sequence. Here, we review some of the most interesting applications of this structural alphabet. Pracoviště Biotechnologický ústav Kontakt Monika Kopřivová, Monika.Koprivova@ibt.cas.cz, Tel.: 325 873 700 Rok sběru 2011
Počet záznamů: 1