Počet záznamů: 1
Analgesic compounds from Scorzonera latifolia (Fisch. and Mey.) DC
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SYSNO ASEP 0352143 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Analgesic compounds from Scorzonera latifolia (Fisch. and Mey.) DC Tvůrce(i) Bahadir, Ö. (TR)
Citoglu, G. S. (TR)
Šmejkal, K. (CZ)
Dall Acqua, S. (IT)
Özbek, H. (TR)
Cvačka, Josef (UOCHB-X) RID, ORCID
Žemlička, M. (CZ)Celkový počet autorů 7 Zdroj.dok. Journal of Ethnopharmacology. - : Elsevier - ISSN 0378-8741
Roč. 131, č. 1 (2010), s. 83-87Poč.str. 5 s. Jazyk dok. eng - angličtina Země vyd. IE - Irsko Klíč. slova Scorzonera latifolia ; analgesic activity ; triterpenes Vědní obor RIV CC - Organická chemie CEZ AV0Z40550506 - UOCHB-X (2005-2011) UT WOS 000281325500011 DOI 10.1016/j.jep.2010.06.003 Anotace A traditional mastic named yakı sakızı prepared from the roots of Scorzonera latifolia DC. is used as a folk remedy for treatment of pain in Turkish folk medicine. The extract of the S. latifolia roots was prepared and subjected to isolation procedures. Writhing and tail-flick tests were used to determine the antinociceptive activity. The n-hexane fraction of the S. latifolia root methanolic extract showed potent antinociceptiveactivity in both writhing and tail-flick tests. Three compounds were isolated using bioassay-guided chromatographic purification. Isolated compounds were triterpene taraxasteryl myristate, taraxasteryl acetate, and fern-7-en-3-b-one, structures were elucidated by means of MS and NMR techniques. Both taraxasterol derivatives showed promising antinociceptive activity when compared to reference compounds. The root extract and the isolated compounds showed promising antinociceptive activities. Pracoviště Ústav organické chemie a biochemie Kontakt asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Viktorie Chládková, Tel.: 232 002 434 Rok sběru 2011
Počet záznamů: 1