Počet záznamů: 1
Adenovirus-derived vectors for prostate cancer gene therapy
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SYSNO ASEP 0351866 Druh ASEP J - Článek v odborném periodiku Zařazení RIV Záznam nebyl označen do RIV Poddruh J Článek ve WOS Název Adenovirus-derived vectors for prostate cancer gene therapy Tvůrce(i) de Vrij, J. (NL)
Willemsen, R. A. (NL)
Lindholm, L. (SE)
Hoeben, R. C. (NL)
Bangma, Ch. H. (NL)
Barber, Ch. (NL)
Behr, J.-P. (FR)
Briggs, S. (SE)
Carlisle, R. (GB)
Cheng, W.-S. (SE)
Dautzenberg, I. J. C. (NL)
de Ridder, C. (NL)
Dzojic, H. (SE)
Erbacher, P. (FR)
Essand, M. (SE)
Fisher, K. (GB)
Frazier, A. (GB)
Georgopoulos, L. J. (GB)
Jennings, I. (GB)
Kochanek, S. (DE)
Koppers-Lalic, D. (NL)
Kraaij, R. (NL)
Kreppel, F. (DE)
Magnusson, M. (SE)
Maitland, N. (GB)
Neuberg, P. (GB)
Nugent, R. (GB)
Ogris, M. (DE)
Remy, J.-S. (FR)
Scaife, M. (GB)
Schenk, E. (NL)
Schooten, E. (NL)
Seymour, L. (GB)
Slade, M. (GB)
Szyjanowicz, P. (GB)
Totterman, T. (SE)
Uil, T. G. (NL)
Ulbrich, Karel (UMCH-V) RID
van der Weel, L. (NL)
van Weerden, W. (NL)
Wagner, E. (DE)
Zuber, G. (FR)Zdroj.dok. Human Gene Therapy. - : Mary Ann Liebert - ISSN 1043-0342
Roč. 21, č. 7 (2010), s. 795-805Poč.str. 11 s. Jazyk dok. eng - angličtina Země vyd. US - Spojené státy americké Klíč. slova adenovirus ; gene delivery ; prostate cancer Vědní obor RIV CD - Makromolekulární chemie UT WOS 000279596700002 DOI 10.1089/hum.2009.203 Anotace Prostate cancer is a leading cause of death among men in Western countries. Whereas the survival rate approaches 100% for patients with localized cancer, the results of treatment in patients with metastasized prostate cancer at diagnosis are much less successful. The patients are usually presented with a variety of treatment options, but therapeutic interventions in prostate cancer are associated with frequent adverse side effects. Gene therapy and oncolytic virus therapy may constitute new strategies. Already a wide variety of preclinical studies has demonstrated the therapeutic potential of such approaches, with oncolytic prostate-specific adenoviruses as the most prominent vector. The state of the art and future prospects of gene therapy in prostate cancer are reviewed, with a focus on adenoviral vectors. We summarize advances in adenovirus technology for prostate cancer treatment and highlight areas where further developments are necessary. Pracoviště Ústav makromolekulární chemie Kontakt Eva Čechová, cechova@imc.cas.cz ; Tel.: 296 809 358 Rok sběru 2011
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