Počet záznamů: 1
Fibrin/Hyaluronic Acid Composite Hydrogels as Appropriate Scaffolds for In Vivo Artificial Cartilage Implantation
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SYSNO ASEP 0351847 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Fibrin/Hyaluronic Acid Composite Hydrogels as Appropriate Scaffolds for In Vivo Artificial Cartilage Implantation Tvůrce(i) Rampichová, Michala (UEM-P) RID, ORCID
Filová, Eva (UEM-P) RID, ORCID
Varga, F. (CZ)
Lytvynets, Andriy (UEM-P)
Prosecká, Eva (UEM-P)
Koláčná, Lucie (UEM-P)
Motlík, Jan (UZFG-Y) RID, ORCID
Nečas, A. (CZ)
Vajner, L. (CZ)
Uhlík, J. (CZ)
Amler, Evžen (UEM-P) RIDZdroj.dok. Asaio Journal - ISSN 1058-2916
Roč. 56, č. 6 (2010), s. 563-568Poč.str. 6 s. Jazyk dok. eng - angličtina Země vyd. US - Spojené státy americké Klíč. slova chondrocyte ; composite scaffold ; osteochondral defect regeneration Vědní obor RIV BO - Biofyzika CEP GAP304/10/1307 GA ČR - Grantová agentura ČR CEZ AV0Z50390512 - UEM-P (2005-2011) AV0Z50390703 - UEM-P (2007-2013) AV0Z50450515 - UZFG-Y (2005-2011) UT WOS 000283719600014 DOI 10.1097/MAT.0b013e3181fcbe24 Anotace Hydrogels prepared from a mixture of fibrin and high-molecular weight (MW) hyaluronic acid (HA) were found to be suitable scaffolds for chondrocyte seeding and pig knee cartilage regeneration. Collagen in the hydrogels is not necessary for the formation of biomechanically stable tissue. Regenerated cartilage showed very good biomechanical and histological properties only 6 months after implantation. Notably, the quality of the healing process was dependent on the initial chondrocyte concentration of the scaffolds. These experiments were performed according to good laboratory practice (GLP). Pracoviště Ústav experimentální medicíny Kontakt Lenka Koželská, lenka.kozelska@iem.cas.cz, Tel.: 241 062 218, 296 442 218 Rok sběru 2011
Počet záznamů: 1