Počet záznamů: 1
Der-p2 (Dermatophagoides pteronyssinus) allergen-like protein from the hard tick Ixodes ricinus - a novel member of ML (MD-2-related lipid-recognition) domain protein family
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SYSNO ASEP 0349082 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Der-p2 (Dermatophagoides pteronyssinus) allergen-like protein from the hard tick Ixodes ricinus - a novel member of ML (MD-2-related lipid-recognition) domain protein family Tvůrce(i) Horáčková, Jana (BC-A)
Rudenko, Natalia (BC-A) RID, ORCID
Golovchenko, Maryna (BC-A) RID, ORCID
Grubhoffer, Libor (BC-A) RID, ORCIDZdroj.dok. Parasitology. - : Cambridge University Press - ISSN 0031-1820
Roč. 137, č. 7 (2010), s. 1139-1149Poč.str. 11 s. Jazyk dok. eng - angličtina Země vyd. GB - Velká Británie Klíč. slova Der-p2 allergen-like protein ; Ixodes ricinus ; tick, ; ML protein family ; IgE-binding activity Vědní obor RIV GJ - Choroby a škůdci zvířat, veterinární medicína CEP GA524/06/1479 GA ČR - Grantová agentura ČR CEZ AV0Z60220518 - PAU-O, BC-A (2005-2011) UT WOS 000279156600010 DOI 10.1017/S0031182009992083 Anotace Analysis of the expression pattern showed that the gene encoding the tick Der-p2 allergen-like protein is strongly induced by the bloodmeal in gut and haemolymph throughout all tick developmental stages. Der-p2 allergenlike protein possesses a putative lipid-binding site, according to the comparisons with the related proteins. The ability of tick Der-p2 allergen-like protein to bind immunoglobulin E (IgE) was revealed. The presence of a putative lipid-binding domain in Der-p2 allergen-like protein and its ability to interact with IgE might indicate the involvement of the protein in the tick’s immune response. Pracoviště Biologické centrum (od r. 2006) Kontakt Dana Hypšová, eje@eje.cz, Tel.: 387 775 214 Rok sběru 2011
Počet záznamů: 1