Počet záznamů: 1
New in vitro reporter gene bioassays for screening of hormonal active compounds in the environment
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SYSNO ASEP 0348168 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název New in vitro reporter gene bioassays for screening of hormonal active compounds in the environment Tvůrce(i) Svobodová, Kateřina (MBU-M) RID
Cajthaml, Tomáš (MBU-M) RID, ORCIDZdroj.dok. Applied Microbiology and Biotechnology. - : Springer - ISSN 0175-7598
Roč. 88, č. 4 (2010), s. 839-847Poč.str. 9 s. Jazyk dok. eng - angličtina Země vyd. DE - Německo Klíč. slova endocrine disruptors ; in vitro bioassays ; reporter gene assays Vědní obor RIV EE - Mikrobiologie, virologie CEP GAP503/10/0408 GA ČR - Grantová agentura ČR CEZ AV0Z50200510 - MBU-M (2005-2011) UT WOS 000282123800004 DOI 10.1007/s00253-010-2833-7 Anotace Identification of chemicals with endocrinedisrupting activities in the past two decades has led to the need for sensitive assays for detection and monitoring of these activities in the environment. In vitro reporter gene assays represent a relatively fast and easy-to-perform method for detection of compounds that are able to bind to hormonal receptors and stimulate or silence their transactivation activity, thus interfering with the hormone signaling pathways. This paper reviews upgrades on reporter gene assays performed during the last decade Pracoviště Mikrobiologický ústav Kontakt Eliška Spurná, eliska.spurna@biomed.cas.cz, Tel.: 241 062 231 Rok sběru 2011
Počet záznamů: 1