Počet záznamů: 1

Hemoglobin adducts in 1,3-butadiene exposed Czech workers: Female–male comparisons

SYSNO ASEP	0347670
Druh ASEP	J - Článek v odborném periodiku
Zařazení RIV	J - Článek v odborném periodiku
Poddruh J	Článek ve WOS
Název	Hemoglobin adducts in 1,3-butadiene exposed Czech workers: Female–male comparisons
Tvůrce(i)	Vacek, P. M. (US) Albertini, R. J. (US) Šrám, Radim (UEM-P)_RID Upton, P. (US) Swenberg, J. A. (US)
Zdroj.dok.	Chemico-Biological Interactions. - : Elsevier - ISSN 0009-2797 Roč. 188, č. 3 (2010), s. 668-676
Poč.str.	9 s.
Jazyk dok.	eng - angličtina
Země vyd.	IE - Irsko
Klíč. slova	3-Butadiene ; metabolism ; THB-Val hemoglobin adducts
Vědní obor RIV	DN - Vliv životního prostředí na zdraví
CEZ	AV0Z50390512 - UEM-P (2005-2011)
UT WOS	000285169100035
EID SCOPUS	78149471572
DOI	10.1016/j.cbi.2010.06.017
Anotace	The results of this study confirm the findings of the previous molecular epidemiological study of female and male 1,3-butadiene (BD) exposed Czech workers, showing that females appeared to absorb or metabolize less BD per unit exposure conc. that did males (based on metabolite conc. in urine). In this study, another biomarker to measure a second metabolite of BD was used. The authors measured production and accumulation of the 1,2-dihydroxy-3,4-epoxybutane (EBD) metabolite as reflected in THB-Val hemoglobin adduct concentrations. In both the control and exposed groups mean THB-Val concentrations were significantly higher for males than females. It was also found that the size of difference increased with exposure.
Pracoviště	Ústav experimentální medicíny
Kontakt	Lenka Koželská, lenka.kozelska@iem.cas.cz, Tel.: 241 062 218, 296 442 218
Rok sběru	2011

Počet záznamů: 1