Počet záznamů: 1
Reduced UVB-induced corneal damage caused by reactive oxygen and nitrogen species and decreased changes in corneal optics after trehalose treatment
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SYSNO ASEP 0347608 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Reduced UVB-induced corneal damage caused by reactive oxygen and nitrogen species and decreased changes in corneal optics after trehalose treatment Tvůrce(i) Čejková, Jitka (UEM-P) RID
Čejka, Čestmír (UEM-P) RID
Ardan, Taras (UEM-P)
Širc, Jakub (UMCH-V) RID, ORCID
Michálek, Jiří (UMCH-V) RID, ORCID
Luyckx, J. (FR)Zdroj.dok. Histology and Histopathology. - : Universidad de Murcia - ISSN 0213-3911
Roč. 25, č. 11 (2010), s. 1403-1416Poč.str. 14 s. Jazyk dok. eng - angličtina Země vyd. ES - Španělsko Klíč. slova UVB rays ; Rabbit cornea ; Trehalose treatment Vědní obor RIV FF - ORL, oftalmologie, stomatologie CEZ AV0Z50390512 - UEM-P (2005-2011) AV0Z40500505 - UMCH-V (2005-2011) UT WOS 000282136800005 Anotace Trehalose, a nonreducing disaccharide of glucose, is synthetized as a stress responsive factor when cells are exposed to various stress conditions. In UVB-irradiated cornea the effect of trehalose was compared with eyes treated with buffered saline during irradiation. Results show that trehalose significantly reduced oxidative damage of the cornea induced by UVB rays. Trehalose reduced changes of corneal optics, suppressed apoptosis of corneal cells and decreased the formation of peroxynitrite, the reaction product between superoxide and nitric oxide. Pracoviště Ústav experimentální medicíny Kontakt Lenka Koželská, lenka.kozelska@iem.cas.cz, Tel.: 241 062 218, 296 442 218 Rok sběru 2011
Počet záznamů: 1