Počet záznamů: 1
Experimental and Theoretical Investigation of the Aromatic-Aromatic Interaction in Isolated Capped Dipeptides
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SYSNO ASEP 0346449 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Experimental and Theoretical Investigation of the Aromatic-Aromatic Interaction in Isolated Capped Dipeptides Tvůrce(i) Gloaguen, E. (FR)
Valdés, H. (ES)
Pagliarulo, F. (FR)
Pollet, R. (FR)
Tardivel, B. (FR)
Hobza, Pavel (UOCHB-X) RID, ORCID
Piuzzi, F. (FR)
Mons, M. (FR)Celkový počet autorů 8 Zdroj.dok. Journal of Physical Chemistry A. - : American Chemical Society - ISSN 1089-5639
Roč. 114, č. 9 (2010), s. 2973-2982Poč.str. 10 s. Jazyk dok. eng - angličtina Země vyd. US - Spojené státy americké Klíč. slova aromatic residues interactions ; Ac-Phe-Phe-NH2 dipeptides ; Ac-Phe-D-Phe-NH2 dipeptides ; correlated ab initio calculations Vědní obor RIV CF - Fyzikální chemie a teoretická chemie CEP LC512 GA MŠMT - Ministerstvo školství, mládeže a tělovýchovy CEZ AV0Z40550506 - UOCHB-X (2005-2011) UT WOS 000275046600004 DOI 10.1021/jp904216f Anotace Among the forces responsible for shaping proteins, interactions between side chains of aromatic residues play an important role as they are involved in the secondary and the tertiary structures of proteins contributing to the formation of hydrophobic domains. The purpose of this paper is to document this interaction in two capped dipeptides modeling a segment of a protein chain having two consecutive Phe residues, Ac-Phe-Phe- NH2 and Ac-Phe-D-Phe-NH2. These two molecules have been investigated in the gas phase by IR/UV double resonance spectroscopy, and the assignment of the observed conformers has been done by comparison with quantum chemistry calculations. Both peptides are found to adopt a-turn type I conformation stabilized by an edge-to-face interaction between the two aromatic rings. Pracoviště Ústav organické chemie a biochemie Kontakt asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Viktorie Chládková, Tel.: 232 002 434 Rok sběru 2011
Počet záznamů: 1