Počet záznamů: 1
High-LET Radiation-Induced Response of Microvessels in the Hippocampus
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SYSNO ASEP 0344033 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název High-LET Radiation-Induced Response of Microvessels in the Hippocampus Tvůrce(i) Mao, X. W. (US)
Favre, C. J. (US)
Fike, J. R. (US)
Kubínová, Lucie (FGU-C) RID, ORCID
Anderson, E. (US)
Campbell-Beachler, M. (US)
Jones, T. (US)
Smith, A. (US)
Rightnar, S. (US)
Nelson, G. A. (US)Zdroj.dok. Radiation Research. - : Radiation Research Society - ISSN 0033-7587
Roč. 173, č. 4 (2010), s. 486-493Poč.str. 8 s. Jazyk dok. eng - angličtina Země vyd. US - Spojené státy americké Klíč. slova hippocampus ; stereology ; microvessels Vědní obor RIV EA - Morfologické obory a cytologie CEZ AV0Z50110509 - FGU-C (2005-2011) UT WOS 000276472800011 DOI 10.1667/RR1728.1 Anotace Endothelial population changes in hippocampal microvessels exposed to 56Fe ions at doses of 0, 0.5, 2 and 4 Gy were quantified using unbiased stereological techniques. Twelve months after exposure, mice that received 0.5 Gy or 2 Gy of iron ions showed a 34% or 29% loss of endothelial cells, respectively, in the hippocampal cornu ammonis region 1 (CA1) compared to age-matched controls or mice that received 4 Gy. In contrast to the CA1, in the dentate gyrus (DG), there was no significant difference in microvessel cell and length density between irradiated groups and age-matched controls. Vascular topology differences between CA1 and DG may account for the variation in dose response Pracoviště Fyziologický ústav Kontakt Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Rok sběru 2011
Počet záznamů: 1