Počet záznamů: 1
No-cGMP Signaling in the Spinal Cord and Brain Stem Circuitry
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SYSNO ASEP 0340868 Druh ASEP M - Kapitola v monografii Zařazení RIV C - Kapitola v knize Název Nitric oxide: A regulator of stem cell proliferation and differentiation Tvůrce(i) Čížková, D. (SK)
Rosocha, J. (SK)
Vanický, I. (SK)
Jergová, S. (SK)
Nagyová, M. (SK)
Juhásová, Jana (UZFG-Y) RID, ORCID
Čížek, M. (SK)Celkový počet autorů 7 Zdroj.dok. No-cGMP Signaling in the Spinal Cord and Brain Stem Circuitry. - Kerala : Transworld Research Network, 2009 / Lukáčová Nadežda - ISBN 978-81-7895-416-5 Rozsah stran s. 27-39 Poč.str. 12 s. Poč.výt. 200 Poč.str.knihy 161 Jazyk dok. eng - angličtina Země vyd. IN - Indie Klíč. slova stem cells ; nitric oxide Vědní obor RIV FH - Neurologie, neurochirurgie, neurovědy CEZ AV0Z50450515 - UZFG-Y (2005-2011) Anotace In recent years, cell replacement strategies,together with endogenous stem cell stimulation within the adult central nervous system, has been considered as a promising therapeutic approach to compensate for destroyed neural pools following various neurological disorders. Therefore, a great deal of effort has been going towards establishing the factors which control cellular survival, proliferation and differentiation. Nitric oxide (NO), a diffusible intracellular, intercellular messenger and powerful mediator in the inflammatory cascade in the mammalian nervous system, has been shown to affect embryonic as well as adult neurogenesis. It has been confirmed by several groups that at physiological concentrations NO derived from the neuronal isoform of NO synthase (nNOS) in nitrergic neurons is a negative regulator of stem/progenitor cell pool proliferation and is most likely needed for initiation of differentiation. Pracoviště Ústav živočišné fyziologie a genetiky Kontakt Jana Zásmětová, knihovna@iapg.cas.cz, Tel.: 315 639 554 Rok sběru 2012
Počet záznamů: 1