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The effect of laparotomy on hydroxyl radicals, singlet oxygen and antioxidants measured by EPR method in the tails of rats
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SYSNO ASEP 0340387 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název The effect of laparotomy on hydroxyl radicals, singlet oxygen and antioxidants measured by EPR method in the tails of rats Tvůrce(i) Fricová, J. (CZ)
Stopka, Pavel (UACH-T) SAI
Křížová, Jana (UACH-T) SAI
Yamamotová, A. (CZ)
Rokyta, R. (CZ)Zdroj.dok. Neuroendocrinology Letters - ISSN 0172-780X
Roč. 30, č. 3 (2009), s. 373-376Poč.str. 4 s. Jazyk dok. eng - angličtina Země vyd. SE - Švédsko Klíč. slova EPR-direct measurement in anesthetized rats ; laparotomy ; visceral pain Vědní obor RIV ED - Fyziologie CEZ AV0Z40320502 - UACH-T (2005-2011) UT WOS 000272199300014 Anotace The aim of the study was to demonstrate that direct measurement of hydroxyl radicals and singlet oxygen in the tail of living rats is possible. The basic level of hydroxyl radicals and singlet oxygen were measured and the effects of antioxidants on their levels were studied in the tail of living anaesthetized rats after acute postoperative pain. Laparotomy was performed as the source of acute abdominal pain. After closure of the abdominal cavity, the animals began to awaken within 30-60 minutes. They were left to recover for 2-3 hours; then they were reanesthetized and the effect of antioxidants was measured on the numbers of hydroxyl radicals and singlet oxygen via blood in the tail. Pracoviště Ústav anorganické chemie Kontakt Jana Kroneislová, krone@iic.cas.cz, Tel.: 311 236 931 Rok sběru 2010
Počet záznamů: 1