Počet záznamů: 1
Sperm antibodies, intra-acrosomal sperm proteins, and cytokines in semen in men from infertile couples
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SYSNO ASEP 0339340 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Sperm antibodies, intra-acrosomal sperm proteins, and cytokines in semen in men from infertile couples Tvůrce(i) Ulčová-Gallová, Z. (CZ)
Gruberová, J. (CZ)
Vrzalová, J. (CZ)
Bibková, K. (CZ)
Pěknicová, Jana (BTO-N) RID
Mičanová, Z. (CZ)
Topolčan, O. (CZ)Celkový počet autorů 7 Zdroj.dok. American Journal of Reproductive Immunology - ISSN 1046-7408
Roč. 61, č. 3 (2009), s. 236-245Poč.str. 15 s. Jazyk dok. eng - angličtina Země vyd. US - Spojené státy americké Klíč. slova intra-acrosomal protein ; cytokines ; infertility Vědní obor RIV EC - Imunologie CEZ AV0Z50520701 - BTO-N (2007-2013) UT WOS 000263345900007 DOI 10.1111/j.1600-0897.2009.00686.x Anotace The aim of this study was to investigate seminal sperm-agglutinating antibodies, intra-acrosomal proteins, sperm head abnormalities, and cytokines in men from infertile couples.The direct mixed anti-immunoglobulin reaction test in semen, and immunocytochemical method using monoclonal antibodies and immunofluorescence for the examination of intra-acrosomal proteins in the spermatozoa were used. Cytokines in seminal plasma were determined by multiplex immunoanalytic xMAP. Sperm-agglutinating antibodiesin seminal plasma were found to be more in astheno- and oligoasthenospermatic men than in normospermatic men. Sperm head pathology and very low amounts of acrosomal proteins were frequently detected in pathologic semen samples. Cytokine levels defined as 'high' were obtained especially for IL-8, IL-5, IL-6,IL-10. The high cellularity in semen was correlated with higher IL-5. Immunologic cause of male infertility is a very important risk factor in the pathogenesis of sperm cells. Pracoviště Biotechnologický ústav Kontakt Monika Kopřivová, Monika.Koprivova@ibt.cas.cz, Tel.: 325 873 700 Rok sběru 2010
Počet záznamů: 1