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Ovarian hyperstimulation syndrome biomarker(s) search in human follicular fluid

SYSNO ASEP	0338300
Druh ASEP	C - Konferenční příspěvek (mezinárodní konf.)
Zařazení RIV	D - Článek ve sborníku
Název	Ovarian hyperstimulation syndrome biomarker(s) search in human follicular fluid
Tvůrce(i)	Jarkovská, Karla (UZFG-Y)_RID Martinková, Jiřina (UZFG-Y) Skalníková, Helena (UZFG-Y)_{RID, ORCID} Hrabáková, Rita (UZFG-Y)_{RID, ORCID} Halada, Petr (MBU-M)_{RID, ORCID} Kavan, Daniel (MBU-M)_{RID, ORCID} Rezábek, K. (CZ) Gadher, S. J. (CH) Kovářová, Hana (UZFG-Y)_{RID, ORCID}
Zdroj.dok.	3rd Central and Eastern Proteomics Conference, 2009. - Budapest : Hungarian proteomic society, 2009 - ISBN 978-963-9319-99-8
Rozsah stran	s. 47-47
Poč.str.	1 s.
Akce	3rd Central and Eastern European Proteomics Conference
Datum konání	06.10.2009-09.10.2009
Místo konání	Budapešť
Země	HU - Maďarsko
Typ akce	EUR
Jazyk dok.	eng - angličtina
Země vyd.	HU - Maďarsko
Klíč. slova	Ovarian hyperstimulation syndrom ; Follicular fluid ; Biomarkers
Vědní obor RIV	FK - Gynekologie a porodnictví
CEP	1QS500450568 GA AV ČR - Akademie věd
CEZ	AV0Z50200510 - MBU-M (2005-2011)
	AV0Z50450515 - UZFG-Y (2005-2011)
Anotace	Ovarian hyperstimulation syndrome (OHSS) is a serious complication of in vitro fertilisation therapy using hormonal stimulation of ovaries. Current diagnosis is not sufficient and could be significantly improved if a protein biomarker(s) could be identified in patient follicular fluid (HFF). In search for new potential diagnostic and prognostic biomarker(s) of OHSS we have used a combination of immunoaffinity depletion, 2-D LC and 2-DE to obtain 2D protein profiles of HFF from OHSS positive and OHSS negative women. The protein maps were evaluated using software tools and protein spots or bands significantly increased or decreased in HFF of OHSS positive and OHSS negative women were identified using MS. In total, we identified 20 proteins and 3 of them were shared between two different 2D technologies. Most of the identified proteins belong to different functional groups including the complement cascade, transport, blood coagulation, acute phase response and inflammation.
Pracoviště	Ústav živočišné fyziologie a genetiky
Kontakt	Jana Zásmětová, knihovna@iapg.cas.cz, Tel.: 315 639 554
Rok sběru	2010

Počet záznamů: 1