Počet záznamů: 1
Evaluation of Antimicrobial and Anti-Inflammatory Activities of Seed Extracts from Six Nigella Species
- 1.
SYSNO ASEP 0335914 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Evaluation of Antimicrobial and Anti-Inflammatory Activities of Seed Extracts from Six Nigella Species Tvůrce(i) Landa, Přemysl (UEB-Q) RID, ORCID
Maršík, Petr (UEB-Q) RID, ORCID
Havlík, J. (CZ)
Klouček, P. (CZ)
Vaněk, Tomáš (UEB-Q) RID, ORCID
Kokoška, L. (CZ)Zdroj.dok. Journal of Medicinal Food - ISSN 1096-620X
Roč. 12, č. 2 (2009), s. 408-415Poč.str. 8 s. Jazyk dok. eng - angličtina Země vyd. US - Spojené státy americké Klíč. slova antimicrobial activity ; cyclooxygenase-1 ; cyclooxygenase-2 Vědní obor RIV EI - Biotechnologie a bionika CEP ME08070 GA MŠMT - Ministerstvo školství, mládeže a tělovýchovy GP525/09/P528 GA ČR - Grantová agentura ČR CEZ AV0Z50380511 - UEB-Q (2005-2011) UT WOS 000266279000023 DOI 10.1089/jmf.2007.0600 Anotace Seed extracts from six species of the genus Nigella (Family Ranunculaceae)-Nigella arvensis, Nigella damascena, Nigella hispanica, Nigella nigellastrum, Nigella orientalis, and Nigella sativa-obtained by successive extraction with n-hexane, chloroform, and methanol, were tested for their antimicrobial activity against 10 strains of pathogenic bacteria and yeast using the microdilution method as well as for anti-inflammatory properties by in vitro cyclooxygenase (COX)-1 and COX-2 assay. Chemical characterization of active extracts was carried out including free and fixed fatty acid analysis. Comparison of antimicrobial activity showed that N. arvensis chloroform extract was the most potent among all species tested, inhibiting Gram-positive bacterial and yeast strains with minimum inhibitory concentration (MIC) values ranging from 0.25 to 1 mg/mL. Pracoviště Ústav experimentální botaniky Kontakt David Klier, knihovna@ueb.cas.cz, Tel.: 220 390 469 Rok sběru 2010
Počet záznamů: 1