Počet záznamů: 1  

Leukotrienes and 8-isoprostane in exhaled breath condensate in bronchoprovocation tests with occupational allergens

  1. 1.
    SYSNO ASEP0312364
    Druh ASEPJ - Článek v odborném periodiku
    Zařazení RIVJ - Článek v odborném periodiku
    Poddruh JČlánek ve WOS
    NázevLeukotrienes and 8-isoprostane in exhaled breath condensate in bronchoprovocation tests with occupational allergens
    Překlad názvuLeukotrieny a 8-isoprostan v kondenzátu vydechovaného vzduchu u bonchoprovokačního testu s pracovními alergeny
    Tvůrce(i) Klusáčková, P. (CZ)
    Lebedová, J. (CZ)
    Kačer, P. (CZ)
    Kuzma, Marek (MBU-M)
    Brabec, Marek (UIVT-O) RID, SAI, ORCID
    Pelclová, D. (CZ)
    Fenclová, Z. (CZ)
    Navrátil, Tomáš (UFCH-W) RID
    Zdroj.dok.Prostaglandins Leukotrienes and Essential Fatty Acids. - : Elsevier - ISSN 0952-3278
    Roč. 78, 4-5 (2008), s. 281-292
    Poč.str.12 s.
    Jazyk dok.eng - angličtina
    Země vyd.GB - Velká Británie
    Klíč. slovaoccupational allergens ; leukotrienes ; 8-isoprostane
    Vědní obor RIVCC - Organická chemie
    CEZAV0Z50200510 - MBU-M (2005-2011)
    AV0Z10300504 - UIVT-O (2005-2011)
    AV0Z40400503 - UFCH-W (2005-2011)
    UT WOS000257596400007
    DOI10.1016/j.plefa.2008.03.006
    AnotaceExhaled breath condensate (EBC) contains many substances, which could help in diagnosis of occupational asthma. The aim of the study is to monitor leukotrienes (LT) and 8-isoprostane from EBC in bronchoprovocation tests with allergens in 47 patients with suspected occupational asthma. Forty-one patients were tested negative. In negative bronchoprovocation tests, no significant differences (P<0.05) were seen between the five measurements during and after the test. In control measurements (without provocation), significant differences were found among four measurements done within 24 h for 8-isoprostane (P=0.0138). The relationship between the log transformed ratios of the EBC parameters and FEV1 was never significant at the 5 level in control measurements, while in negative tests, statistical significance was recorded for LTB4 (P=0.0299) before and 5 h after the test. Six of 47 patients were tested positive
    PracovištěMikrobiologický ústav
    KontaktEliška Spurná, eliska.spurna@biomed.cas.cz, Tel.: 241 062 231
    Rok sběru2009