Počet záznamů: 1
Arrangement of chromosome 11 and 22 territories, EWSR1 and FLI1 genes, and other genetic elements of these chromosomes in human lymphocytes and Ewing sarcoma cells
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SYSNO ASEP 0127067 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Ostatní články Název Arrangement of chromosome 11 and 22 territories, EWSR1 and FLI1 genes, and other genetic elements of these chromosomes in human lymphocytes and Ewing sarcoma cells Tvůrce(i) Taslerová, R. (CZ)
Kozubek, Stanislav (BFU-R) RID
Lukášová, Emilie (BFU-R) RID, ORCID
Jirsová, Pavla (BFU-R)
Bártová, Eva (BFU-R) ORCID
Kozubek, Michal (BFU-R)Zdroj.dok. Human Genetics - ISSN 0340-6717
Roč. 112, č. 2 (2003), s. 143-155Poč.str. 13 s. Jazyk dok. eng - angličtina Země vyd. US - Spojené státy americké Klíč. slova high-resolution cytometry ; human leukemic cells ; Ewing sarcoma cells Vědní obor RIV BO - Biofyzika CEP NC5955 GA MZd - Ministerstvo zdravotnictví IBS5004010 GA AV ČR - Akademie věd GA301/01/0186 GA ČR - Grantová agentura ČR CEZ AV0Z5004920 - BFU-R Anotace Standard and repeated fluorescence in situ hybridization and high-resolution cytometry were used to study topographical parameters of chromosome 11 and 22 territories, EWSR1 and FLI1 genes, and other genetic elements of these chromosomes in human lymphocytes and Ewing sarcoma cells. HSA 11 and its elements (BCL1, FLI1, centromere) were found, on average, more peripherally in comparison with HSA 22 and investigated elements (BCR, EWSR1, centromere). After the elimination of fluctuations of chromosome territories in nuclear volume, it was found that genetic elements in most cases adhered to their territories. The investigated genetic elements of HSA 11 were found close to each other relative to the large molecular lengths among them. This finding indicates a higher degree of chromatin condensation of at least a part of HSA 11 compared with HSA 22. Pracoviště Biofyzikální ústav Kontakt Jana Poláková, polakova@ibp.cz, Tel.: 541 517 244 Rok sběru 2004
Počet záznamů: 1