Matrices of ferromagnetic microwires for the control of cellular dynamics and localized delivery of medicines

0521437 - FZÚ 2020 RIV RU eng J - Článek v odborném periodiku
Beklemisheva, A.V. - Yudanov, N.A. - Gurevich, A.A. - Panina, L.V. - Zablotskyy, Vitaliy A. - Deyneka, Alexander
Matrices of ferromagnetic microwires for the control of cellular dynamics and localized delivery of medicines.
Physics of Metals and Metallography. Roč. 120, č. 6 (2019), s. 556-562. ISSN 0031-918X. E-ISSN 1555-6190
Grant CEP: GA MŠMT(CZ) EF16_019/0000760
Grant ostatní: OP VVV - SOLID21(XE) CZ.02.1.01/0.0/0.0/16_019/0000760
Institucionální podpora: RVO:68378271
Klíčová slova: diamagnetic capture * paramagnetic capture * ferromagnetic microwires
Obor OECD: Condensed matter physics (including formerly solid state physics, supercond.)
Impakt faktor: 1.064, rok: 2019
Způsob publikování: Omezený přístup
https://doi.org/10.1134/s0031918x19060036

A microwire in a biocompatible shell can be introduced into soft tissues or into blood vessels to maintain the biofunctioning of magnetic nanoparticles or stem cells with magnetic markers circulating in the blood. The magnetic fields created by the lattices of microwires are characterized by strong spatial gradients and can change over time in a specified manner. Such fields are necessary for the development of various magnetophoretic analytical chips for controlling the kinetics of cells and also for controlled drug delivery. A system of diametrically magnetized microwires is suggested in this paper, which possesses an energy minimum necessary for the stable capture of diamagnetic cells. The suggested dipole system is also promising for the accelerated diffusion transfer of magnetic nanoparticles, which are located in a liquid carrier, due to a gradient magnetic field.
Trvalý link: http://hdl.handle.net/11104/0306060