Frustrated Lewis pairs-assisted reduction of carbonyl compounds

0443293 - ÚOCHB 2016 RIV GB eng J - Článek v odborném periodiku
Marek, Aleš - Pedersen, M. H. F.
Frustrated Lewis pairs-assisted reduction of carbonyl compounds.
Tetrahedron. Roč. 71, č. 6 (2015), s. 917-921. ISSN 0040-4020. E-ISSN 1464-5416
Institucionální podpora: RVO:61388963
Klíčová slova: frustrated Lewis pairs * hydrogen activation * benzyl alcohol * tritium labeling * labeled compounds
Kód oboru RIV: CC - Organická chemie
Impakt faktor: 2.645, rok: 2015

An alternative and robust method for the reduction of carbonyl groups by frustrated Lewis pairs (FLPs) is reported in this paper. With its very mild reaction conditions, good to excellent yields, absolute regioselectivity and the non-metallic character of the reagent, it provides an excellent tool for H-1, H-2 as well as H-3 chemistry. It is a new strategy for the one-pot synthesis of aromatic alcohols selectively labeled with heavy isotopes of hydrogen.
Trvalý link: http://hdl.handle.net/11104/0246072