Development of radiometric assays for quantification of enzyme activities of the key enzymes of thyroid hormones metabolism

0431267 - FGÚ 2015 RIV CZ eng J - Článek v odborném periodiku
Pavelka, Stanislav
Development of radiometric assays for quantification of enzyme activities of the key enzymes of thyroid hormones metabolism.
Physiological Research. Roč. 63, Suppl.1 (2014), S133-S140. ISSN 0862-8408. E-ISSN 1802-9973
Grant CEP: GA MŠMT(CZ) 7AMB12SK158; GA ČR(CZ) GA304/08/0256
Institucionální podpora: RVO:67985823
Klíčová slova: enzyme * metabolism * radiometric assay * thyroid hormone
Kód oboru RIV: FB - Endokrinologie, diabetologie, metabolizmus, výživa
Impakt faktor: 1.293, rok: 2014

We newly elaborated and adapted several radiometric enzyme assays for the determination of activities of the key enzymes engaged in the biosynthesis and metabolic transformations of thyroid hormones (THs) in the thyroid gland and in peripheral tissues, especially in white adipose tissue. These radiometric assays proved to be very useful tools for studies of factors modulating THs metabolism, not only in model animals but also in clinical studies of human obesity
Trvalý link: http://hdl.handle.net/11104/0235840