Biomedical properties of laser prepared silver-doped hydroxyapatite

0365044 - FZÚ 2012 RIV RU eng J - Článek v odborném periodiku
Jelínek, Miroslav - Weiserová, Marie - Kocourek, Tomáš - Zezulová, Markéta - Strnad, D.
Biomedical properties of laser prepared silver-doped hydroxyapatite.
Laser Physics. Roč. 21, č. 7 (2011), 1265-1269. ISSN 1054-660X. E-ISSN 1555-6611
Grant CEP: GA ČR GA204/07/0325
Výzkumný záměr: CEZ:AV0Z10100522; CEZ:AV0Z50200510
Klíčová slova: silver-doped hydroxyapatite * PLD * layers * antibacterial properties
Kód oboru RIV: BH - Optika, masery a lasery
Impakt faktor: 3.605, rok: 2011

Thin films of hydroxyapatite (HA) and silver- doped HA were synthesized using KrF excimer laser deposition. Material was ablated from one target composed from silver and HA segments. Layers properties as silver content, structure, color, FTIR spectra and antibacterial properties (Gram-positive Bacillus subtilis) were measured. Silver concentration in HA layers of 0.06, 0.3, 1.2, 4.4, 8.3, and 13.7 at % was detected. The antibacterial efficacy changed with silver dopation from 71.0 to 99.9%. The focus is on investigation of min- imum Ag concentration needed to reach a high antibacterial efficacy.
Trvalý link: http://hdl.handle.net/11104/0200382