Unapparent Microsporidial Infection among Immunocompetent Humans in the Czech Republic

0359390 - BC 2012 RIV US eng J - Článek v odborném periodiku
Sak, Bohumil - Brady, D. - Pelikánová, M. - Květoňová, Dana - Rost, M. - Kostka, Martin - Tolarová, V. - Hůzová, Z. - Kváč, Martin
Unapparent Microsporidial Infection among Immunocompetent Humans in the Czech Republic.
Journal of Clinical Microbiology. Roč. 49, č. 3 (2011), s. 1064-1070. ISSN 0095-1137. E-ISSN 1098-660X
Grant CEP: GA AV ČR KJB500960701; GA ČR GA206/09/0927
Výzkumný záměr: CEZ:AV0Z60220518
Klíčová slova: ENCEPHALITOZOON SEPTATA INTESTINALIS * ENTEROCYTOZOON-BIENEUSI INFECTION * IMMUNODEFICIENCY-VIRUS-INFECTION * DIARRHEA * HIV * PREVALENCE * CUNICULI * PARASITES * AIDS * INDIVIDUALS
Kód oboru RIV: GJ - Choroby a škůdci zvířat, veterinární medicína
Impakt faktor: 4.153, rok: 2011

In the present population-based study, we determined the prevalences of the most common human-pathogenic microsporidia, Encephalitozoon spp. and Enterocytozoon bieneusi, in asymptomatic healthy people living in the Czech Republic. A total of 382 males and females (ages, 1 to 84 years) of whom 265 were Czech nationals and 117 were foreign students, were included in a study testing for the presence of microsporidia by use of coprology and molecular methods. 4 genotypes of 3 human-pathogenic Encephalitozoon spp. and 7 E. bieneusi genotypes, including 3 novel genotypes, were detected. Some of these were reported in humans for the first time. The highest prevalence was recorded for individuals older than 50 years and for loose, unformed stool samples. These findings clearly show that exposure to microsporidia is common among immunocompetent people and that microsporidiosis is not linked to any clinical manifestation in healthy populations.
Trvalý link: http://hdl.handle.net/11104/0197184