Rebound increase in seizure susceptibility but not isolation-induced calls after single administration of clonazepam and Ro 19-8022 in infant rats

0358971 - FGÚ 2012 RIV US eng J - Článek v odborném periodiku
Mikulecká, Anna - Mareš, Pavel - Kubová, Hana
Rebound increase in seizure susceptibility but not isolation-induced calls after single administration of clonazepam and Ro 19-8022 in infant rats.
Epilepsy and Behavior. Roč. 20, č. 1 (2011), s. 12-19. ISSN 1525-5050. E-ISSN 1525-5069
Grant CEP: GA ČR(CZ) GA305/09/0846
Výzkumný záměr: CEZ:AV0Z50110509
Klíčová slova: Pentylenetetrazole-induced seizure * ultrasonic vocalization * motor performance * Clonazepam * Ro 19-8022 * immature rats
Kód oboru RIV: FH - Neurologie, neurochirurgie, neurovědy
Impakt faktor: 2.335, rok: 2011

Clonazepam and Ro 19-8022 administration led to rebound phenomena in immature 12-day-old rats. Ultrasonic vocalizations were suppressed after both drugs. Dissociation between rebound proconvulsant and anxiolytic-like effects was found
Trvalý link: http://hdl.handle.net/11104/0196861