Počet záznamů: 1
Alpha-cyclodextrins reversibly capped with disulfide bonds
- 1.0350020 - ÚOCHB 2011 RIV GB eng J - Článek v odborném periodiku
Kumprecht, Lukáš - Buděšínský, Miloš - Bouř, Petr - Kraus, Tomáš
Alpha-cyclodextrins reversibly capped with disulfide bonds.
New Journal of Chemistry. Roč. 34, č. 10 (2010), s. 2254-2260. ISSN 1144-0546. E-ISSN 1369-9261
Grant CEP: GA AV ČR IAA400550810
Výzkumný záměr: CEZ:AV0Z40550506
Klíčová slova: cyclodextrins * disulfide bond * dynamic covalent bond
Kód oboru RIV: CC - Organická chemie
Impakt faktor: 2.631, rok: 2010
Per-O-methyl-6I, 6IV-disulfanyl-6I, 6IV-dideoxy-alpha-cyclodextrin undergoes air-oxidation at pH 9 to exclusively form monomeric species having an intramolecular disulfide linkage capping the C6I and C6IV positions. Molecular models show that the disulfide bridge effectively closes the primary rim of the the cyclodextrin cavity and can be cleaved by reduction with dithiothreitol. Thus, the macrocyclic system can interchange the open-ended and cup-like forms by application of external stimuli.
Trvalý link: http://hdl.handle.net/11104/0190124
Počet záznamů: 1