Počet záznamů: 1
New bradykinin B-2 receptor antagonists - influence of C-terminal segment modifications on their pharmacological properties
- 1.0347364 - ÚOCHB 2011 RIV PL eng J - Článek v odborném periodiku
Sleszynska, M. - Kwiatkowska, A. - Sobolewski, D. - Wierzba, T. H. - Katarzynska, J. - Zabrocki, J. - Borovičková, Lenka - Slaninová, Jiřina - Prahl, A.
New bradykinin B-2 receptor antagonists - influence of C-terminal segment modifications on their pharmacological properties.
Acta Biochimica Polonica. Roč. 56, č. 4 (2009), s. 641-648. ISSN 0001-527X. E-ISSN 1734-154X
Výzkumný záměr: CEZ:AV0Z40550506
Klíčová slova: bradykinin
Kód oboru RIV: CC - Organická chemie
Impakt faktor: 1.262, rok: 2009
Analogues of the bradykinin antagonist [D-Arg(0),Hyp(3),Thi(5,8),D-Phe(7)]BK having in position 7 or 8 L-pipecolic acid or L-beta(2)-isoproline or L-beta(3)-homoproline and free or acylated N-terminal amino group were synthesized and biologically evaluated (isolated rat uterus and rat blood pressure tests). The results thus support the hypothesis about the existence of different types of BK receptors in the rat uterus and blood vessels.
Trvalý link: http://hdl.handle.net/11104/0188157
Počet záznamů: 1