Spatio-temporal changes of SDF1 and its CXCR4 receptor in the dorsal root ganglia following unilateral sciatic nerve injury as a model of neuropathic pain

0347087 - BFÚ 2011 RIV US eng J - Článek v odborném periodiku
Dubový, P. - Klusáková, I. - Svíženská, I. - Brázda, Václav
Spatio-temporal changes of SDF1 and its CXCR4 receptor in the dorsal root ganglia following unilateral sciatic nerve injury as a model of neuropathic pain.
Histochemistry and Cell Biology. Roč. 133, č. 3 (2010), s. 323-337. ISSN 0948-6143. E-ISSN 1432-119X
Grant ostatní: GA ČR(CZ) GA309/07/0121
Výzkumný záměr: CEZ:AV0Z50040507; CEZ:AV0Z50040702
Klíčová slova: chemokine * satellite glial cells * chronic constriction injury
Kód oboru RIV: BO - Biofyzika
Impakt faktor: 4.727, rok: 2010

There is a growing evidence that chemokines and their receptors play a role in inducing and maintaining neuropathic pain. In the present study, unilateral chronic constriction injury (CCI) of rat sciatic nerve was used to investigate changes for stromal derived factor-1 (SDF1) and its CXCR4 receptor in lumbal and cervical dorsal root ganglia from both sides of naive, operated and sham-operated rats.
Trvalý link: http://hdl.handle.net/11104/0187944