Effect of estrogens on boar sperm capacitation in vitro

0346620 - BTÚ 2011 RIV GB eng J - Článek v odborném periodiku
Děd, Lukáš - Dostálová, Pavla - Dorosh, Andriy - Dvořáková-Hortová, K. - Pěknicová, Jana
Effect of estrogens on boar sperm capacitation in vitro.
Reproductive Biology and Endocrinology. Roč. 8, - (2010), ---. E-ISSN 1477-7827
Grant CEP: GA MŠMT(CZ) 1M06011; GA ČR(CZ) GD523/08/H064; GA ČR(CZ) GA523/09/1793
Výzkumný záměr: CEZ:AV0Z50520701
Klíčová slova: capacitation * acrosome reaction * monoclonal antibody * estrogen * flow cytometry
Kód oboru RIV: EI - Biotechnologie a bionika
Impakt faktor: 1.695, rok: 2010

Mammalian sperm must undergo a series of controlled molecular processes in the female reproductive tract called capacitation before they are capable of penetrating and fertilizing the egg. The purpose of this study is to investigate the effect of three natural estrogens such as estrone (E1), 17beta-estradiol (E2) and estriol (E3) as well as the synthetical one, 17alpha-ethynylestradiol (EE2) on boar sperm capacitation in vitro. We demonstrate here the general stimulatory effect of four different estrogens on boar sperm capacitation. The effect further highly depends on different reactivity of individual animals. Our experimental data further contribute to our knowledge about steroidal action in sperm.
Trvalý link: http://hdl.handle.net/11104/0187600