Inactivation of the left auditory cortex impairs temporal discrimination in the rat

0345711 - ÚEM 2011 RIV NL eng J - Článek v odborném periodiku
Rybalko, Natalia - Šuta, Daniel - Popelář, Jiří - Syka, Josef
Inactivation of the left auditory cortex impairs temporal discrimination in the rat.
Behavioural Brain Research. Roč. 209, č. 1 (2010), s. 123-130. ISSN 0166-4328. E-ISSN 1872-7549
Grant CEP: GA ČR GA309/07/1336; GA MŠMT(CZ) LC554
Výzkumný záměr: CEZ:AV0Z50390512
Klíčová slova: auditory cortex * temporal discrimination * hemispheric lateralization
Kód oboru RIV: FH - Neurologie, neurochirurgie, neurovědy
Impakt faktor: 3.393, rok: 2010
http://arl-repository.lib.cas.cz/uloziste_av/UEM-P/cav_un_epca-0345711_01.pdf

The ability of rats to detect or discriminate a series of gaps in continuous noise under conditions of unilateral or bilateral reversible inactivation of the auditory cortex (AC) is studied with the aim to explore the hemispheric lateralization of acoustical signal processing in non-human mammals. The results showed that muscimol-induced reversible inactivation of the left AC suppresses the ability of rats to discriminate between acoustical stimuli of different temporal parameters, whereas inactivation of the right AC results in no change or only a mild decrease in discrimination ability. Our findings demonstrate that, similarly as in humans, the left AC in the rat plays the dominant role in temporal discrimination.
Trvalý link: http://hdl.handle.net/11104/0186916