Soluble form of carbonic anhydrase IX (CA IX) in the serum and urine of renal carcinoma patients

0191607 - UMG-J 20033112 RIV GB eng J - Článek v odborném periodiku
Závada, Jan - Závadová, Zuzana - Zaťovičová, M. - Hyršl, L. - Kawaciuk, I.
Soluble form of carbonic anhydrase IX (CA IX) in the serum and urine of renal carcinoma patients.
British Journal of Cancer. Roč. 89, - (2003), s. 1067-1071. ISSN 0007-0920. E-ISSN 1532-1827
Grant CEP: GA ČR GA301/99/0356
Výzkumný záměr: CEZ:AV0Z5052915
Klíčová slova: carbonic anhydrase IX * tumor antigens * cancer diagnostics
Kód oboru RIV: EC - Imunologie
Impakt faktor: 3.894, rok: 2003

Tumor-associated protein CA IX has two major forms. One is a cell-associated, transmembrane protein of 54/58 kDa, expressed in gastric mucosa and in several types of cancer. The other is a soluble protein s-CA IX (50/54 kDa) released into body fluids. Conceivably, s-CA IX might serve as a marker antigen for monitoring certain groups of cancer patients after surgery and/or chemotherapy.
Trvalý link: http://hdl.handle.net/11104/0087347