Tumour-inhibitory effects of dendritic cells administered at the site of HPV 16-induced neoplasms

0191464 - UMG-J 20023041 RIV CZ eng J - Článek v odborném periodiku
Mendoza, Luis - Bubeník, Jan - Šímová, Jana - Korb, Jan - Bieblová, Jana - Vonka, V. - Indrová, Marie - Mikyšková, Romana - Jandlová, Táňa
Tumour-inhibitory effects of dendritic cells administered at the site of HPV 16-induced neoplasms.
Folia Biologica. Roč. 48, č. 3 (2002), s. 114-119. ISSN 0015-5500. E-ISSN 0015-5500
Grant CEP: GA MZd NC7148; GA ČR GA301/00/0114; GA AV ČR IAA7052002; GA AV ČR IAA5052203
Výzkumný záměr: CEZ:AV0Z5052915
Klíčová slova: HPV 16 * dendritic cells * adjuvant therapy
Kód oboru RIV: EB - Genetika a molekulární biologie
Impakt faktor: 0.615, rok: 2002

It was examined whether administration of APC at the site od HPV 16-associated tumours can inhibit their growth and whether the efficacy of esteblished DC lines is comparable to that of fresh BMDC. The result suggest that local increase in the number of DC can inhibit progression of tumours and that DC may be used for delivery of therapeutic vaccines against HPV 16 neoplasms. The efficacy of established lines and fresh DC was comparable.
Trvalý link: http://hdl.handle.net/11104/0087216