Stereoselective Hydrogenation of Methylacetoacetate in Microfluidic Chip Reactor in Presence of [N8222][Tf2N] Ionic Liquid.

0480381 - ÚCHP 2018 HU eng C - Konferenční příspěvek (zahraniční konf.)
Hejda, Stanislav - Klusoň, Petr - Stavárek, Petr - Pěnkavová, Věra - Vychodilová, Hana - Bendová, Magdalena
Stereoselective Hydrogenation of Methylacetoacetate in Microfluidic Chip Reactor in Presence of [N8222][Tf2N] Ionic Liquid.
Final Programme & Book of Abstracts. Veszprém: OOK-Press, 2017, s. 49. ISBN 978-615-5270-41-3.
[Conference on Frontiers in Organic Synthesic Technology /6./. Budapest (HU), 18.10.2017-20.10.2017]
Grant CEP: GA ČR GA15-04790S
Institucionální podpora: RVO:67985858
Klíčová slova: stereoselectivity * microfluidic chip * chiral catalyst
Obor OECD: Chemical process engineering

In this study, we focused on the application of a microfluidic chip reactor (MR, Chemtrix 3222 and 3223) to the stereoselective hydrogenation of methylacetoacetate (MAA) to isomeric (R)-(+) or (S)-(-)-methyl-3-hydroxybutanoates (MHB) over a chiral ([RuCl((R)-BINAP)(p-cymene)]Cl) complex immobilized in the mixed [N8222][Tf2N]/methanol/water solvent phase.
Trvalý link: http://hdl.handle.net/11104/0276162