Progress in biocatalysis with immobilized viable whole cells: systems development, reaction engineering and applications

0479465 - ÚPT 2018 RIV NL eng J - Článek v odborném periodiku
Polakovič, M. - Švitel, J. - Bučko, M. - Filip, J. - Neděla, Vilém - Ansorge-Schumacher, M.B. - Gemeiner, P.
Progress in biocatalysis with immobilized viable whole cells: systems development, reaction engineering and applications.
Biotechnology Letters. Roč. 39, č. 5 (2017), s. 667-683. ISSN 0141-5492. E-ISSN 1573-6776
Institucionální podpora: RVO:68081731
Klíčová slova: biocatalysis * immobilization methods * immobilized whole-cell biocatalyst * multienzyme cascade reactions * process economics * reaction engineering
Obor OECD: Bioprocessing technologies (industrial processes relying on biological agents to drive the process) biocatalysis, fermentation
Impakt faktor: 1.846, rok: 2017

Viable microbial cells are important biocatalysts in the production of fine chemicals and biofuels, in environmental applications and also in emerging applications such as biosensors or medicine. Their increasing significance is driven mainly by the intensive development of high performance recombinant strains supplying multienzyme cascade reaction pathways, and by advances in preservation of the native state and stability of whole-cell biocatalysts throughout their application. In many cases, the stability and performance of whole-cell biocatalysts can be highly improved by controlled immobilization techniques. This review summarizes the current progress in the development of immobilized whole-cell biocatalysts, the immobilization methods as well as in the bioreaction engineering aspects and economical aspects of their biocatalytic applications.
Trvalý link: http://hdl.handle.net/11104/0275459