Generation of NPS for Exposure Experiments from Copper Acetylacetone.

0465384 - ÚCHP 2017 RIV CZ eng C - Konferenční příspěvek (zahraniční konf.)
Moravec, Pavel - Schwarz, Jaroslav - Vodička, Petr - Kupčík, Jaroslav - Švehla, Jaroslav
Generation of NPS for Exposure Experiments from Copper Acetylacetone.
Sborník XVII. výroční konference České aerosolové společnosti. Praha: Czech Aerosol Society, 2016 - (Mašková, L.), s. 95-100. ISBN 978-80-86186-85-6.
[Výroční konference České aerosolové společnosti /17./. Mikulov (CZ), 25.10.2016-26.10.2016]
Grant CEP: GA ČR(CZ) GBP503/12/G147
Institucionální podpora: RVO:67985858
Klíčová slova: copper acetylacetonate * hot wall reactor * nanoparticle generation
Kód oboru RIV: CF - Fyzikální chemie a teoretická chemie
http://cas.icpf.cas.cz/download/Sbornik_VKCAS_2016.pdf

Particles containing copper are emitted from smelters, iron foundries, power stations, and municipal incinerators (WHO, 1998) and also from brake linings during breaking, Kukutschová et al. (2011). Nanoparticles (NPs) of copper are ingredients in polymers, inks, and bioactive coatings inhibiting the growth of microorganisms, Cioffi at al. (2005), and CuO NPs has been used in antimicrobial textiles, Gabbay and Borkow (2006), therefore they can be easily inhaled. Even though CuO NPs were found highly toxic, Karlsson et al. (2008), in vivo studies of their toxicity are still rather rare. In this work we tested a method of long lasting nanoparticle generation from copper
acetylacetonate (CuAA) for use in follow up exposure experiments with laboratory animals. The exposure chamber for inhalation experiments was constructed in the
Institute of Analytical Chemistry AS CR (Večeřa et al., 2011) and some methods of NPs generation for these experiments were already tested in our laboratory (Moravec et al., 2015, Moravec et al., 2016).
Trvalý link: http://hdl.handle.net/11104/0263980