Selected ion flow tube, SIFT, studies of the reactions of H3O+, NO+ and O2 + with some biologically active isobaric compounds in preparation for SIFT-MS analyses

0359553 - ÚFCH JH 2015 RIV NL eng J - Článek v odborném periodiku
Smith, D. - Chippendale, T. W. E. - Španěl, Patrik
Selected ion flow tube, SIFT, studies of the reactions of H3O+, NO+ and O2 + with some biologically active isobaric compounds in preparation for SIFT-MS analyses.
International Journal of Mass Spectrometry. Roč. 303, 2-3 (2011), s. 81-89. ISSN 1387-3806. E-ISSN 1873-2798
Grant CEP: GA ČR GA202/09/0800; GA ČR GA203/09/0256
Výzkumný záměr: CEZ:AV0Z40400503
Klíčová slova: SIFT-MS * ion-molecule reactions * proton transfers
Kód oboru RIV: CF - Fyzikální chemie a teoretická chemie
Impakt faktor: 2.549, rok: 2011

A study of the reactions of H3O+, NO+ and O2+ ions with two groups of four isobaric, biologically active compounds with molecular weights, MW, of 86u and 88u has been carried out using the selected ion flow tube, SIFT, technique in preparation for the analyses of these compounds in the headspace of bacterial and cell cultures using SIFT-MS. These compounds are: MW 86u: 2,3 butanedione (diacetyl), C4H6O2; allyl ethyl ether, C5H10O, cyclopropane carboxylic acid, C4H6O2: γ-butyrolactone, C4H6O2. MW 88u: 3-hydroxybutanone (acetoin), C4H8O2; n-butyric acid, C4H8O2; ethyl acetate, C4H8O2; pyruvic acid, C3H4O3. All 24 reactions proceed at the gas kinetic rate, the dominant primary product ions of the H3O+ reactions being the protonated reactant molecules, MH+ with a common mass-to-charge ratio, m/z, in each group of isobaric compounds;...
Trvalý link: http://hdl.handle.net/11104/0197324