Partial genomic structure, mutation analysis and mapping of the porcine inhibitor of DNA binding genes ID1, ID2, ID3 and ID4

0347633 - ÚŽFG 2011 GB eng J - Článek v odborném periodiku
Stratil, Antonín - Horák, Pavel - Filkuková, Jitka - Van Poucke, M. - Bartenschlager, H. - Peelman, L. J. - Geldermann, H.
Partial genomic structure, mutation analysis and mapping of the porcine inhibitor of DNA binding genes ID1, ID2, ID3 and ID4.
Animal Genetics. Roč. 41, - (2010), s. 558-559. ISSN 0268-9146. E-ISSN 1365-2052
Grant CEP: GA ČR(CZ) GA523/06/1302; GA ČR GA523/09/0844
Výzkumný záměr: CEZ:AV0Z50450515
Klíčová slova: genomic structure * muscle-specific genes * porcine
Kód oboru RIV: GI - Šlechtění a plemenářství hospodářských zvířat
Impakt faktor: 2.203, rok: 2010

ID proteins (ID1, ID2, ID3 and ID4) are believed to play a regulatory role during myogenesis. Genomic fragments containing the complete coding sequences of porcine ID1, ID2, ID3 and ID4 genes were amplified by PCR and sequenced. Single nucleotide polymorphisms (SNPs) and indels were found in ID2, ID3 and ID4. The four genes were mapped by radiation hybrid mapping and linkage analysis in the Hohenheim three-generation families to SSC17, SSC3, SSC6 and SSC7, respectively.
Trvalý link: http://hdl.handle.net/11104/0188371