The effect of nonsteroidal anti-inflammatory drugs ibuprofen, flurbiprofen, and diclofenac on in vitro and in vivo growth of mouse fibrosarcoma

0126748 - BFU-R 20023047 RIV US eng J - Článek v odborném periodiku
Hoferová, Zuzana - Fedoročko, P. - Hofmanová, Jiřina - Hofer, Michal - Znojil, V. - Minksová, Kateřina - Souček, Karel - Egyed, A. - Kozubík, Alois
The effect of nonsteroidal anti-inflammatory drugs ibuprofen, flurbiprofen, and diclofenac on in vitro and in vivo growth of mouse fibrosarcoma.
Cancer Investigation. Roč. 20, č. 4 (2002), s. 490-498. ISSN 0735-7907. E-ISSN 1532-4192
Grant CEP: GA AV ČR IBS5004009
Grant ostatní: VEGA MŠ SR(SK) 1/6026/99
Výzkumný záměr: CEZ:AV0Z5004920
Klíčová slova: cyclooxygenase (COX) inhibitors * fibrosarcoma cells
Kód oboru RIV: BO - Biofyzika
Impakt faktor: 1.850, rok: 2002

Three different cyclooxygenase (COX) inhibitors were found to inhibit growth of transplanted fibrosarcoma in mice. Their antitumor effect is supposed to comprise both direct action of COX inhibitors on fibrosarcoma cells and indirect effects that are presumably mediated by extratumoral sources.
Trvalý link: http://hdl.handle.net/11104/0024976