A eukaryotic-type signalling system of Pseudomonas aeruginosa contributes to oxidative

0367286 - MBÚ 2012 RIV GB eng J - Článek v odborném periodiku
Goldová, Jana - Ulrych, Aleš - Hercík, Kamil - Branny, Pavel
A eukaryotic-type signalling system of Pseudomonas aeruginosa contributes to oxidative.
BMC Genomics. Roč. 12, - (2011), s. 1-21. ISSN 1471-2164. E-ISSN 1471-2164
Grant CEP: GA ČR GA204/08/0783
Výzkumný záměr: CEZ:AV0Z50200510
Klíčová slova: SERINE/THREONINE PROTEIN-KINASE * MYCOBACTERIUM-TUBERCULOSIS * ESCHERICHIA-COLI
Kód oboru RIV: EE - Mikrobiologie, virologie
Impakt faktor: 4.073, rok: 2011

The genome of Pseudomonas aeruginosa contains at least three genes encoding eukaryotic-type Ser/Thr protein kinases, one of which, ppkA, has been implicated in P. aeruginosa virulence. Together with the adjacent pppA phosphatase gene, they belong to the type VI secretion system (H1-T6SS) locus, which is important for bacterial pathogenesis. To determine the biological function of this protein pair, we prepared a pppA-ppkA double mutant and characterised its phenotype and transcriptomic profiles
Trvalý link: http://hdl.handle.net/11104/0202024