Opportunistic nature of the mammalian microsporidia: experimental transmission of Trachipleistophora extenrec (Fungi: Microsporidia) between mammalian and insect hosts

0364796 - BC 2012 RIV DE eng J - Článek v odborném periodiku
Vávra, Jiří - Kamler, M. - Modrý, David - Koudela, Břetislav
Opportunistic nature of the mammalian microsporidia: experimental transmission of Trachipleistophora extenrec (Fungi: Microsporidia) between mammalian and insect hosts.
Parasitology Research. Roč. 108, č. 6 (2011), 1565-1573. ISSN 0932-0113. E-ISSN 1432-1955
Grant CEP: GA ČR GD524/03/H133; GA ČR GA524/07/1003
Výzkumný záměr: CEZ:AV0Z60220518
Klíčová slova: NOSEMA-ALGERAE * BRACHIOLA-ALGERAE * AIDS PATIENT * HOMINIS * INFECTION * PATHOGEN * DIPTERA * ULTRASTRUCTURE * CULICIDAE * SEQUENCES
Kód oboru RIV: GJ - Choroby a škůdci zvířat, veterinární medicína
Impakt faktor: 2.149, rok: 2011

Spores of Trachipleistophora extenrec, originally isolated from the muscles of the Madagascan insectivore Hemicentetes semispinosus and maintained by serial passage in SCID mice, were fed to larvae of the Egyptian cotton leafworm Spodoptera littoralis. Extensive infection of larval tissues ensued and caused larval and pupal mortality. The development of T. extenrec in the insect host, studied both by light and electron microscopy, followed generally the same life cycle as in the mammalian host. However, some differences in the fine structure of the parasite were found. Spores isolated from the insect host caused infection of SCID mice when injected intramuscularly. Our results suggest that T. extenrec may be originally an insect microsporidian. This is corroborated by its structural similarity and phylogenetic relationship to 2 other microsporidia having insects either as unique hosts (Vavraia culicis) or being able to infect both mammalian and insect host (Trachipleistophora hominis)
Trvalý link: http://hdl.handle.net/11104/0200181