Počet záznamů: 1
Numerical modelling of microRNA-mediated mRNA decay identifies novel mechanism of microRNA controlled mRNA downregulation
- 1.0351524 - MBÚ 2011 RIV GB eng J - Článek v odborném periodiku
Vohradský, Jiří - Pánek, Josef - Vomastek, Tomáš
Numerical modelling of microRNA-mediated mRNA decay identifies novel mechanism of microRNA controlled mRNA downregulation.
Nucleic Acids Research. Roč. 38, č. 14 (2010), s. 4579-4585. ISSN 0305-1048. E-ISSN 1362-4962
Grant CEP: GA ČR GA310/07/1009; GA ČR GA303/09/0475; GA AV ČR IAA500200716
Výzkumný záměr: CEZ:AV0Z50200510
Klíčová slova: GENE-REGULATION * TRANSLATIONAL REPRESSION * TARGET PREDICTIONS
Kód oboru RIV: EE - Mikrobiologie, virologie
Impakt faktor: 7.836, rok: 2010
A numerical model of miRNAmediated mRNA downregulation and its application to analysis of temporal microarray data of HepG2 cells transfected with miRNA-124a. Using the model analysis revealed a novel mechanism of mRNA accumulation control by miRNA, predicting that specific mRNAs are controlled in a digital, switch-like manner
Trvalý link: http://hdl.handle.net/11104/0191260
Počet záznamů: 1