The slower the better: how sperm capacitation and acrosome reaction is modified in the presence of estrogens

0370076 - BTÚ 2013 RIV GB eng J - Článek v odborném periodiku
Šebková, N. - Černá, M. - Děd, Lukáš - Pěknicová, Jana - Dvořáková-Hortová, K.
The slower the better: how sperm capacitation and acrosome reaction is modified in the presence of estrogens.
Reproduction. Roč. 143, č. 3 (2012), s. 297-307. ISSN 1470-1626
Grant CEP: GA MŠMT(CZ) 1M06011
Výzkumný záměr: CEZ:AV0Z50520701
Klíčová slova: sperm capacitation * estrogen * phosphorylation
Kód oboru RIV: ED - Fyziologie
Impakt faktor: 3.555, rok: 2012

It has been demonstrated that both natural and synthetical estrogens can modify the physiological progress of mouse sperm capacitation. The potential risk in the procapacitation effect of estrogens can also be seen in the decreased ability of sperm to undergo the acrosome reaction. In conclusion, the capacitating ability of sperm can be significantly lowered by increasing the level of estrogens in the environment.
Trvalý link: http://hdl.handle.net/11104/0203984