Počet záznamů: 1
Implantation of ultrathin, biofunctionalized polyimide membranes into the subretinal space of rats
- 1.0360808 - MBÚ 2012 RIV GB eng J - Článek v odborném periodiku
Julien, S. - Julien, T. - Ziemssen, F. - Arango-Gonzalez, B. - Beck, S. - Thielecke, H. - Bueth, H. - van Vlierberghe, S. - Šírová, Milada - Rossmann, Pavel - Říhová, Blanka - Schacht, E. - Dubruel, P. - Zrenner, E. - Schraermeyer, U.
Implantation of ultrathin, biofunctionalized polyimide membranes into the subretinal space of rats.
Biomaterials. Roč. 32, č. 16 (2011), s. 3890-3898. ISSN 0142-9612. E-ISSN 1878-5905
Výzkumný záměr: CEZ:AV0Z50200510
Klíčová slova: Ophthalmology * Biocompatibility * Cell viability
Kód oboru RIV: EC - Imunologie
Impakt faktor: 7.404, rok: 2011
Subretinal implants aim to replace the photoreceptor function in patients suffering from degenerative retinal disease by topically applying electrical stimuli in the subretinal space. Critical obstacles in the design of high-resolution subretinal implants include the proximity of stimulating electrodes to the target cells and enabling nutrient flow between the retina and the choroid. The present work evaluates the adhesion, migration and survival of retinal cells on an ultrathin (5 mu m), highly porous (circle divide 1 mu m spaced 3 gm), gelatin-coated polyimide (PI) membrane
Trvalý link: http://hdl.handle.net/11104/0006502
Počet záznamů: 1