Ergot alkaloids as chiral selectors in capillary electrophoresis and other electromigration methods

0354230 - MBÚ 2011 RIV IN eng J - Článek v odborném periodiku
Sinibaldi, M. - Messina, A. - Stodůlková, Eva - Flieger, Miroslav
Ergot alkaloids as chiral selectors in capillary electrophoresis and other electromigration methods.
Global Journal of Analytical Chemistry. Roč. 1, č. 3 (2010), s. 233-243. ISSN 0976-5514
Výzkumný záměr: CEZ:AV0Z50200510
Klíčová slova: capillary electrophoresis * capillary electrochromatography * chiral analysis
Kód oboru RIV: CB - Analytická chemie, separace

This review surveys the accomplishments in enantioseparations by capillary electrophoresis and other lectromigration methods obtained using the semisynthetic ergot alkaloid derivative - terguride and its analogues as the chiral selectors. These selectors exhibited a marked discrimination towards carboxylic groups containing compounds under specific experimental conditions (BGE or buffer pH, % of organic modifier in the mobile phase) hat enhanced stereoselective interactions of the selectant with basic functions of the ergoline skeleton. Substituents in N(1) and urea side chain of terguride affected the discriminative process
Trvalý link: http://hdl.handle.net/11104/0193279