Modulation of type I iodothyronine 5’-deiodinase activity in white adipose tissue by nutrition: possible involvement of leptin

0347895 - FGÚ 2011 RIV CZ eng J - Článek v odborném periodiku
Macek Jílková, Zuzana - Pavelka, Stanislav - Flachs, Pavel - Hensler, Michal - Kůs, Vladimír - Kopecký, Jan
Modulation of type I iodothyronine 5’-deiodinase activity in white adipose tissue by nutrition: possible involvement of leptin.
Physiological Research. Roč. 59, č. 4 (2010), s. 561-569. ISSN 0862-8408. E-ISSN 1802-9973
Grant CEP: GA ČR(CZ) GD305/08/H037; GA MŠMT(CZ) OC08007
Výzkumný záměr: CEZ:AV0Z50110509
Klíčová slova: adipose tissue * thyroid hormones * obesity
Kód oboru RIV: FB - Endokrinologie, diabetologie, metabolizmus, výživa
Impakt faktor: 1.646, rok: 2010

Our objective was to describe possible changes in activities of TH-metabolizing enzymes in white adipose tissue, and the role of TH metabolism in the tissue during obesogenic treatment, caloric restriction and in response to leptin in mice. Our results suggest a functional role for D1 in white adipose tissue, with D1 possibly being involved in the control of adipose tissue metabolism and/or accumulation of the tissue
Trvalý link: http://hdl.handle.net/11104/0188565