Delineation of a New Species of the Borrelia burgdorferi Sensu Lato Complex, Borrelia americana sp. nov

0335286 - BC 2010 RIV US eng J - Článek v odborném periodiku
Rudenko, Natalia - Golovchenko, Maryna - Lin, T. - Gao, L. - Grubhoffer, Libor - Oliver, J. H., Jr.
Delineation of a New Species of the Borrelia burgdorferi Sensu Lato Complex, Borrelia americana sp. nov.
Journal of Clinical Microbiology. Roč. 47, č. 12 (2009), s. 3875-3880. ISSN 0095-1137. E-ISSN 1098-660X
Grant CEP: GA MŠMT(CZ) LC06009
Výzkumný záměr: CEZ:AV0Z60220518
Klíčová slova: multilocus sequence analysis * B. burgdorferi sl complex * new borrelia species * Borrelia americana
Kód oboru RIV: GJ - Choroby a škůdci zvířat, veterinární medicína
Impakt faktor: 4.162, rok: 2009

Analysis of Borrelia isolates collected from ticks, birds, and rodents from the southeastern United States revealed the presence of well-established populations of Borrelia burgdorferi sensu stricto, Borrelia bissettii, Borrelia carolinensis, and Borrelia sp. nov. Multilocus sequence analysis of 5 genomic loci from 7 samples from South Carolina representing Borrelia sp. nov. showed their close relatedness to California strains known as genomospecies 1 and separation from any other known species of the B. burgdorferi sl complex. The sequences of all analyzed isolates share the same RFLP patterns of the 5S-23S intergenic spacer region and contain unique signature nucleotides in the 16S rRNA gene. We propose that 7 Borrelia sp. nov. isolates from South Carolina and 2 California isolates designated as genomospecies 1 comprise a single species, which we name Borrelia americana sp. nov. All strains are associated with Ixodes pacificus or Ixodes minor and their rodent and bird hosts.
Trvalý link: http://hdl.handle.net/11104/0179793