Počet záznamů: 1
Degradation of phospholipids under different types of irradiation and varying oxygen saturation
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SYSNO ASEP 0487625 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Degradation of phospholipids under different types of irradiation and varying oxygen saturation Tvůrce(i) Vyšín, Luděk (FZU-D) RID, ORCID
Tomanová, K. (CZ)
Pavelková, T. (CZ)
Wagner, Richard (UJF-V)
Davídková, Marie (UJF-V) RID, ORCID, SAI
Múčka, V. (CZ)
Čuba, V. (CZ)
Juha, Libor (FZU-D) RID, ORCID, SAICelkový počet autorů 8 Zdroj.dok. Radiation and Environmental Biophysics - ISSN 0301-634X
Roč. 56, č. 3 (2017), s. 241-247Poč.str. 7 s. Jazyk dok. eng - angličtina Země vyd. DE - Německo Klíč. slova lipid peroxidation ; DOPC ; gamma rays ; eectrons ; protons ; oxygen saturation Vědní obor RIV BO - Biofyzika Obor OECD Biophysics CEP GA13-28721S GA ČR - Grantová agentura ČR GBP108/12/G108 GA ČR - Grantová agentura ČR LM2015056 GA MŠMT - Ministerstvo školství, mládeže a tělovýchovy Institucionální podpora FZU-D - RVO:68378271 ; UJF-V - RVO:61389005 UT WOS 000405925500004 EID SCOPUS 85019203496 DOI https://doi.org/10.1007/s00411-017-0693-6 Anotace The effects of different types of radiation on the formation of peroxide forms of 2-dioleoyl-sn-glycero-3-phosphocholine were studied under various conditions. For the irradiation, an aqueous solution of small unilamellar vesicles was prepared. Variations in parameters such as the dose rate and molecular oxygen saturation levels were evaluated. Our study suggests that the mechanism of the peroxides formation process remains unchanged under irradiation by accelerated electrons, gamma and accelerated protons. The values of radiation chemical yields of the peroxidic form depend on the type of radiation, dose rate, and the saturation of molecular oxygen. The level of oxygen saturation strongly affects the values of radiation chemical yields as well, as the dissolved oxygen is an important agent participating in peroxidation and it is a source of free radicals during the radiolysis. The values of radiation chemical yields strongly suggest that the mechanism of radiation-induced peroxidation of phosphatidylcholines does not proceed via chain reaction. Pracoviště Fyzikální ústav Kontakt Kristina Potocká, potocka@fzu.cz, Tel.: 220 318 579 Rok sběru 2018
Počet záznamů: 1