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Toxoplasmosis in at-risk groups of patients
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SYSNO ASEP 0469018 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Toxoplasmosis in at-risk groups of patients Tvůrce(i) Kučerová, Petra (UZFG-Y)
Červinková, Monika (UZFG-Y)Zdroj.dok. Reviews in Medical Microbiology - ISSN 0954-139X
Roč. 27, č. 1 (2016), s. 13-19Poč.str. 7 s. Forma vydání Tištěná - P Jazyk dok. eng - angličtina Země vyd. US - Spojené státy americké Klíč. slova congenital toxoplasmosis ; immunosuppression ; infection Vědní obor RIV EE - Mikrobiologie, virologie CEP ED2.1.00/03.0124 GA MŠMT - Ministerstvo školství, mládeže a tělovýchovy Institucionální podpora UZFG-Y - RVO:67985904 UT WOS 000385532200003 EID SCOPUS 84952775476 DOI https://doi.org/10.1097/MRM.0000000000000057 Anotace Toxoplasmosis, one of the most common parasitic zoonoses worldwide caused by the protozoan Toxoplasma gondii, is found all over the world, and can affect any warm-blooded animal, including humans, although the primary host is the cat. Disease transmission occurs from eating undercooked lamb, beef or pork, ingestion of soil, drinking contaminated water, those undergoing blood transfusion or organ transplantation, transplacental transfer from mother to foetus and during careless handling of cat litter. The highest prevalence (about 55%) in Europe is seen in France and Greece. Toxoplasmosis is usually asymptomatic or is characterized by mild flu-like symptoms in healthy people. Pregnant women and immunosuppressed patients (HIV/AIDS patients) may develop serious health problems. Symptomatic patients usually suffer from malaise, headache, low-grade fever and cervical lymphadenopathy, but in severe cases, there can be manifestations such as encephalitis, myocarditis or hepatitis. In immunosuppressed patients testing positive for the parasite, there is risk of reactivation of infection. In these persons, it is recommended that biological specimens are examined using PCR or histological staining; in a case of central nervous system infection, detection of parasite DNA in brain biopsies using molecular biological methods. Toxoplasmosis acquired during pregnancy means high risk of damage for the foetus. It is necessary to determine whether the infection was received before or after pregnancy began. Paediatric toxoplasmosis can either be congenital or postnatally acquired; although little is known about postnatally acquired toxoplasmosis, congenital toxoplasmosis can be the consequence of transplacental haematogenous infection of the foetus during primary infection of the pregnant woman. Pracoviště Ústav živočišné fyziologie a genetiky Kontakt Jana Zásmětová, knihovna@iapg.cas.cz, Tel.: 315 639 554 Rok sběru 2017
Počet záznamů: 1